| Sluis to Savignano sul Rubicone | 650.41 mi (1,046.74 km) |
| Sluis to Savona | 538.05 mi (865.90 km) |
| Sluis to Scafati | 901.92 mi (1,451.50 km) |
| Sluis to Scalea | 992.64 mi (1,597.50 km) |
| Sluis to Scandiano | 573.40 mi (922.80 km) |
| Sluis to Scandicci | 635.56 mi (1,022.83 km) |
| Sluis to Schio | 531.04 mi (854.62 km) |
| Sluis to Sciacca | 1,064.80 mi (1,713.62 km) |
| Sluis to Scicli | 1,146.69 mi (1,845.42 km) |
| Sluis to Scordia | 1,118.65 mi (1,800.30 km) |
| Sluis to Scorze | 562.26 mi (904.87 km) |
| Sluis to Sedico | 534.60 mi (860.35 km) |
| Sluis to Sedriano | 476.68 mi (767.15 km) |
| Sluis to Segni | 806.03 mi (1,297.18 km) |
| Sluis to Segrate | 484.51 mi (779.74 km) |
