| South Lyon to Sacile | 4,457.05 mi (7,172.92 km) |
| South Lyon to Sala Consilina | 4,814.65 mi (7,748.43 km) |
| South Lyon to Salemi | 4,809.49 mi (7,740.13 km) |
| South Lyon to Salerno | 4,768.12 mi (7,673.55 km) |
| South Lyon to Salo | 4,394.23 mi (7,071.82 km) |
| South Lyon to Salsomaggiore Terme | 4,403.04 mi (7,086.01 km) |
| South Lyon to Saluzzo | 4,308.60 mi (6,934.03 km) |
| South Lyon to Salzano | 4,459.47 mi (7,176.83 km) |
| South Lyon to Samarate | 4,323.71 mi (6,958.35 km) |
| South Lyon to San Benedetto del Tronto | 4,635.99 mi (7,460.90 km) |
| South Lyon to San Biagio di Callalta | 4,463.69 mi (7,183.62 km) |
| South Lyon to San Bonifacio | 4,431.90 mi (7,132.46 km) |
| South Lyon to San Casciano in Val di Pesa | 4,498.02 mi (7,238.87 km) |
| South Lyon to San Cataldo | 4,874.35 mi (7,844.52 km) |
| South Lyon to San Cesareo | 4,639.58 mi (7,466.68 km) |
