| South Lyon to Savignano sul Rubicone | 4,529.09 mi (7,288.86 km) |
| South Lyon to Savona | 4,362.12 mi (7,020.16 km) |
| South Lyon to Scafati | 4,755.37 mi (7,653.04 km) |
| South Lyon to Scalea | 4,848.31 mi (7,802.60 km) |
| South Lyon to Scandiano | 4,440.34 mi (7,146.03 km) |
| South Lyon to Scandicci | 4,494.23 mi (7,232.76 km) |
| South Lyon to Schio | 4,422.37 mi (7,117.12 km) |
| South Lyon to Sciacca | 4,835.10 mi (7,781.35 km) |
| South Lyon to Scicli | 4,935.31 mi (7,942.61 km) |
| South Lyon to Scordia | 4,919.17 mi (7,916.64 km) |
| South Lyon to Scorze | 4,457.61 mi (7,173.83 km) |
| South Lyon to Sedico | 4,435.41 mi (7,138.10 km) |
| South Lyon to Sedriano | 4,336.22 mi (6,978.48 km) |
| South Lyon to Segni | 4,654.05 mi (7,489.97 km) |
| South Lyon to Segrate | 4,349.14 mi (6,999.27 km) |
