| South Portland to Savignano sul Rubicone | 3,930.48 mi (6,325.50 km) |
| South Portland to Savona | 3,755.14 mi (6,043.32 km) |
| South Portland to Scafati | 4,145.61 mi (6,671.72 km) |
| South Portland to Scalea | 4,237.55 mi (6,819.67 km) |
| South Portland to Scandiano | 3,840.17 mi (6,180.16 km) |
| South Portland to Scandicci | 3,890.85 mi (6,261.71 km) |
| South Portland to Schio | 3,830.06 mi (6,163.88 km) |
| South Portland to Sciacca | 4,207.73 mi (6,771.69 km) |
| South Portland to Scicli | 4,308.95 mi (6,934.59 km) |
| South Portland to Scordia | 4,295.20 mi (6,912.46 km) |
| South Portland to Scorze | 3,866.41 mi (6,222.39 km) |
| South Portland to Sedico | 3,847.30 mi (6,191.63 km) |
| South Portland to Sedriano | 3,736.78 mi (6,013.77 km) |
| South Portland to Segni | 4,044.85 mi (6,509.56 km) |
| South Portland to Segrate | 3,750.53 mi (6,035.89 km) |
