| South Portland to Selargius | 3,963.81 mi (6,379.14 km) |
| South Portland to Selvazzano Dentro | 3,859.27 mi (6,210.89 km) |
| South Portland to Senago | 3,740.55 mi (6,019.84 km) |
| South Portland to Senigallia | 3,979.04 mi (6,403.64 km) |
| South Portland to Seravezza | 3,841.18 mi (6,181.79 km) |
| South Portland to Seregno | 3,741.18 mi (6,020.85 km) |
| South Portland to Seriate | 3,761.96 mi (6,054.28 km) |
| South Portland to Sermoneta | 4,048.36 mi (6,515.21 km) |
| South Portland to Serramanna | 3,946.78 mi (6,351.73 km) |
| South Portland to Serravalle Pistoiese | 3,870.45 mi (6,228.88 km) |
| South Portland to Sessa Aurunca | 4,101.59 mi (6,600.87 km) |
| South Portland to Sesto Calende | 3,714.39 mi (5,977.73 km) |
| South Portland to Sesto Fiorentino | 3,888.52 mi (6,257.98 km) |
| South Portland to Sesto San Giovanni | 3,746.46 mi (6,029.34 km) |
| South Portland to Sestri Levante | 3,795.65 mi (6,108.51 km) |
