| South Portland to Enniskillen | 2,834.14 mi (4,561.11 km) |
| South Portland to Epping | 3,192.89 mi (5,138.46 km) |
| South Portland to Epsom | 3,185.93 mi (5,127.26 km) |
| South Portland to Erdington | 3,096.66 mi (4,983.60 km) |
| South Portland to Erith | 3,200.72 mi (5,151.06 km) |
| South Portland to Esher | 3,181.18 mi (5,119.62 km) |
| South Portland to Euxton | 3,041.15 mi (4,894.26 km) |
| South Portland to Evesham | 3,101.18 mi (4,990.87 km) |
| South Portland to Evington | 3,125.33 mi (5,029.73 km) |
| South Portland to Ewell | 3,186.34 mi (5,127.92 km) |
| South Portland to Exeter | 3,065.16 mi (4,932.90 km) |
| South Portland to Exmouth | 3,072.16 mi (4,944.17 km) |
| South Portland to Failsworth | 3,064.39 mi (4,931.66 km) |
| South Portland to Falkirk | 2,959.11 mi (4,762.23 km) |
| South Portland to Falmouth | 3,012.68 mi (4,848.44 km) |
