| South Portland to Scarborough | 3,118.17 mi (5,018.21 km) |
| South Portland to Scartho | 3,145.03 mi (5,061.43 km) |
| South Portland to Scunthorpe | 3,122.33 mi (5,024.90 km) |
| South Portland to Seacombe | 3,031.81 mi (4,879.23 km) |
| South Portland to Seacroft | 3,085.83 mi (4,966.16 km) |
| South Portland to Seaford | 3,214.09 mi (5,172.57 km) |
| South Portland to Seaham | 3,071.38 mi (4,942.90 km) |
| South Portland to Sedgley | 3,084.87 mi (4,964.62 km) |
| South Portland to Selby | 3,101.87 mi (4,991.97 km) |
| South Portland to Selsey | 3,178.30 mi (5,114.98 km) |
| South Portland to Selston | 3,107.01 mi (5,000.24 km) |
| South Portland to Sevenoaks | 3,205.77 mi (5,159.18 km) |
| South Portland to Shanklin | 3,164.74 mi (5,093.16 km) |
| South Portland to Sheerness | 3,225.23 mi (5,190.51 km) |
| South Portland to Sheffield | 3,094.04 mi (4,979.38 km) |
