| South Portland to Stanmore | 3,177.63 mi (5,113.90 km) |
| South Portland to Stannington | 3,091.15 mi (4,974.72 km) |
| South Portland to Stansted Mountfitchet | 3,192.02 mi (5,137.07 km) |
| South Portland to Stanwell | 3,174.86 mi (5,109.44 km) |
| South Portland to Stapleford | 3,110.91 mi (5,006.52 km) |
| South Portland to Staveley | 3,101.08 mi (4,990.70 km) |
| South Portland to Stepney | 3,190.82 mi (5,135.13 km) |
| South Portland to Stevenage | 3,175.81 mi (5,110.98 km) |
| South Portland to Stevenston | 2,927.40 mi (4,711.20 km) |
| South Portland to Stirling | 2,951.63 mi (4,750.19 km) |
| South Portland to Stockport | 3,066.67 mi (4,935.32 km) |
| South Portland to Stocksbridge | 3,087.49 mi (4,968.83 km) |
| South Portland to Stockton-on-Tees | 3,077.11 mi (4,952.13 km) |
| South Portland to Stoke Gifford | 3,088.78 mi (4,970.92 km) |
| South Portland to Stoke-on-Trent | 3,073.27 mi (4,945.95 km) |
