| South Portland to Darby (Pennsylvania) | 362.26 mi (583.00 km) |
| South Portland to Dardenne Prairie (Missouri) | 1,111.57 mi (1,788.89 km) |
| South Portland to Darien (Illinois) | 906.20 mi (1,458.38 km) |
| South Portland to Davenport (Iowa) | 1,040.58 mi (1,674.65 km) |
| South Portland to Davidson (North Carolina) | 793.62 mi (1,277.21 km) |
| South Portland to Davie (Florida) | 1,336.25 mi (2,150.48 km) |
| South Portland to Davis (California) | 2,658.73 mi (4,278.82 km) |
| South Portland to Dayton (Nevada) | 2,532.28 mi (4,075.31 km) |
| South Portland to Dayton (Ohio) | 764.13 mi (1,229.75 km) |
| South Portland to Daytona Beach (Florida) | 1,161.90 mi (1,869.89 km) |
| South Portland to De Pere (Wisconsin) | 883.66 mi (1,422.11 km) |
| South Portland to De Witt (New York) | 294.00 mi (473.15 km) |
| South Portland to Dearborn (Michigan) | 658.97 mi (1,060.51 km) |
| South Portland to Dearborn Heights (Michigan) | 662.11 mi (1,065.56 km) |
| South Portland to DeBary (Florida) | 1,187.70 mi (1,911.42 km) |
