| South Portland to Eagan (Minnesota) | 1,131.79 mi (1,821.45 km) |
| South Portland to Eagle (Idaho) | 2,273.02 mi (3,658.08 km) |
| South Portland to Eagle Mountain (Utah) | 2,132.77 mi (3,432.36 km) |
| South Portland to Eagle Pass (Texas) | 1,957.95 mi (3,151.01 km) |
| South Portland to Easley (South Carolina) | 894.67 mi (1,439.83 km) |
| South Portland to East Bakersfield (California) | 2,618.29 mi (4,213.73 km) |
| South Portland to East Bethel (Minnesota) | 1,131.77 mi (1,821.40 km) |
| South Portland to East Chicago (Indiana) | 881.52 mi (1,418.67 km) |
| South Portland to East Cleveland (Ohio) | 591.88 mi (952.53 km) |
| South Portland to East Glenville (New York) | 190.48 mi (306.55 km) |
| South Portland to East Grand Rapids (Michigan) | 770.82 mi (1,240.51 km) |
| South Portland to East Hemet (California) | 2,571.42 mi (4,138.31 km) |
| South Portland to East Highland Park (Virginia) | 559.53 mi (900.48 km) |
| South Portland to East Honolulu (Hawaii) | 5,091.46 mi (8,193.92 km) |
| South Portland to East Islip (New York) | 249.57 mi (401.65 km) |
