| South Portland to El Segundo (California) | 2,638.11 mi (4,245.63 km) |
| South Portland to El Sobrante (California) | 2,592.66 mi (4,172.49 km) |
| South Portland to Eldersburg (Maryland) | 451.54 mi (726.68 km) |
| South Portland to Elfers (Florida) | 1,269.03 mi (2,042.31 km) |
| South Portland to Elgin (Illinois) | 918.52 mi (1,478.22 km) |
| South Portland to Elizabeth (New Jersey) | 286.16 mi (460.53 km) |
| South Portland to Elizabeth City (North Carolina) | 596.39 mi (959.80 km) |
| South Portland to Elizabethton (Tennessee) | 807.34 mi (1,299.28 km) |
| South Portland to Elizabethtown (Kentucky) | 911.84 mi (1,467.46 km) |
| South Portland to Elizabethtown (Pennsylvania) | 403.60 mi (649.53 km) |
| South Portland to Elk City (Oklahoma) | 1,644.27 mi (2,646.19 km) |
| South Portland to Elk Grove (California) | 2,645.38 mi (4,257.33 km) |
| South Portland to Elk Grove Village (Illinois) | 902.42 mi (1,452.31 km) |
| South Portland to Elk Plain (Washington) | 2,493.28 mi (4,012.55 km) |
| South Portland to Elk River (Minnesota) | 1,149.46 mi (1,849.87 km) |
