| South Portland to Friendly (Maryland) | 483.10 mi (777.48 km) |
| South Portland to Friendswood (Texas) | 1,680.97 mi (2,705.26 km) |
| South Portland to Frisco (Texas) | 1,599.12 mi (2,573.53 km) |
| South Portland to Front Royal (Virginia) | 522.76 mi (841.30 km) |
| South Portland to Fruit Cove (Florida) | 1,123.01 mi (1,807.31 km) |
| South Portland to Fruita (Colorado) | 1,998.18 mi (3,215.77 km) |
| South Portland to Fruitville (Florida) | 1,314.71 mi (2,115.83 km) |
| South Portland to Fuller Heights (Florida) | 1,265.41 mi (2,036.48 km) |
| South Portland to Fullerton (California) | 2,615.54 mi (4,209.30 km) |
| South Portland to Fullerton (Pennsylvania) | 337.22 mi (542.71 km) |
| South Portland to Fulshear (Texas) | 1,703.11 mi (2,740.89 km) |
| South Portland to Fulton (Missouri) | 1,168.90 mi (1,881.16 km) |
| South Portland to Fulton (New York) | 307.91 mi (495.54 km) |
| South Portland to Fuquay-Varina (North Carolina) | 714.99 mi (1,150.67 km) |
| South Portland to Gadsden (Alabama) | 1,073.30 mi (1,727.30 km) |
