| South San Francisco to Sesena | 5,811.87 mi (9,353.31 km) |
| South San Francisco to Sestao | 5,677.87 mi (9,137.64 km) |
| South San Francisco to Sevilla | 5,865.04 mi (9,438.87 km) |
| South San Francisco to Sevilla La Nueva | 5,787.63 mi (9,314.30 km) |
| South San Francisco to Silla | 5,968.93 mi (9,606.06 km) |
| South San Francisco to Silleda | 5,518.43 mi (8,881.05 km) |
| South San Francisco to Sitges | 5,949.81 mi (9,575.29 km) |
| South San Francisco to Socuellamos | 5,885.53 mi (9,471.84 km) |
| South San Francisco to Soller | 6,057.35 mi (9,748.37 km) |
| South San Francisco to Solsona | 5,900.49 mi (9,495.93 km) |
| South San Francisco to Son Servera | 6,087.70 mi (9,797.21 km) |
| South San Francisco to Sonseca | 5,822.49 mi (9,370.40 km) |
| South San Francisco to Sopelana | 5,675.29 mi (9,133.49 km) |
| South San Francisco to Soria | 5,773.78 mi (9,292.00 km) |
| South San Francisco to Suances | 5,635.10 mi (9,068.81 km) |
