| South San Francisco to Eckington | 5,235.22 mi (8,425.26 km) |
| South San Francisco to Edgware | 5,351.19 mi (8,611.91 km) |
| South San Francisco to Edinburgh | 5,054.79 mi (8,134.90 km) |
| South San Francisco to Edmonton | 5,357.30 mi (8,621.74 km) |
| South San Francisco to Egg Buckland | 5,293.94 mi (8,519.77 km) |
| South San Francisco to Elgin | 4,970.56 mi (7,999.35 km) |
| South San Francisco to Elland | 5,203.04 mi (8,373.48 km) |
| South San Francisco to Ellesmere Port | 5,191.93 mi (8,355.60 km) |
| South San Francisco to Ellon | 5,017.07 mi (8,074.19 km) |
| South San Francisco to Eltham | 5,369.19 mi (8,640.88 km) |
| South San Francisco to Ely | 5,327.55 mi (8,573.87 km) |
| South San Francisco to Emsworth | 5,369.91 mi (8,642.04 km) |
| South San Francisco to Enfield | 5,355.15 mi (8,618.28 km) |
| South San Francisco to Enfield Lock | 5,355.93 mi (8,619.54 km) |
| South San Francisco to Englefield Green | 5,351.86 mi (8,612.99 km) |
