| South San Francisco to Altus (Oklahoma) | 1,302.55 mi (2,096.26 km) |
| South San Francisco to Alum Rock (California) | 38.11 mi (61.33 km) |
| South San Francisco to Alvin (Texas) | 1,656.42 mi (2,665.75 km) |
| South San Francisco to Amarillo (Texas) | 1,154.68 mi (1,858.28 km) |
| South San Francisco to Amelia (Ohio) | 2,056.95 mi (3,310.35 km) |
| South San Francisco to American Canyon (California) | 37.38 mi (60.15 km) |
| South San Francisco to American Fork (Utah) | 600.15 mi (965.85 km) |
| South San Francisco to Americus (Georgia) | 2,184.04 mi (3,514.87 km) |
| South San Francisco to Ames (Iowa) | 1,549.69 mi (2,493.98 km) |
| South San Francisco to Amherst (Ohio) | 2,138.09 mi (3,440.93 km) |
| South San Francisco to Ammon (Idaho) | 679.82 mi (1,094.06 km) |
| South San Francisco to Amsterdam (New York) | 2,532.53 mi (4,075.72 km) |
| South San Francisco to Anacortes (Washington) | 748.63 mi (1,204.80 km) |
| South San Francisco to Anaheim (California) | 367.22 mi (590.98 km) |
| South San Francisco to Anchorage (Alaska) | 1,989.29 mi (3,201.45 km) |
