| South San Francisco to Anoka (Minnesota) | 1,581.68 mi (2,545.47 km) |
| South San Francisco to Ansonia (Connecticut) | 2,607.94 mi (4,197.08 km) |
| South San Francisco to Antelope (California) | 93.19 mi (149.97 km) |
| South San Francisco to Anthem (Arizona) | 634.00 mi (1,020.33 km) |
| South San Francisco to Antioch (California) | 40.77 mi (65.62 km) |
| South San Francisco to Antioch (Illinois) | 1,833.59 mi (2,950.88 km) |
| South San Francisco to Apache Junction (Arizona) | 678.41 mi (1,091.80 km) |
| South San Francisco to Apex (North Carolina) | 2,394.59 mi (3,853.72 km) |
| South San Francisco to Apollo Beach (Florida) | 2,404.95 mi (3,870.40 km) |
| South San Francisco to Apopka (Florida) | 2,423.67 mi (3,900.52 km) |
| South San Francisco to Apple Valley (California) | 361.83 mi (582.31 km) |
| South San Francisco to Apple Valley (Minnesota) | 1,586.15 mi (2,552.66 km) |
| South San Francisco to Appleton (Wisconsin) | 1,819.28 mi (2,927.85 km) |
| South San Francisco to Arbutus (Maryland) | 2,450.29 mi (3,943.36 km) |
| South San Francisco to Arcadia (California) | 345.32 mi (555.74 km) |
