| South San Francisco to Clarksdale (Mississippi) | 1,789.37 mi (2,879.72 km) |
| South San Francisco to Clarkston (Georgia) | 2,142.92 mi (3,448.70 km) |
| South San Francisco to Clarksville (Indiana) | 1,983.21 mi (3,191.68 km) |
| South San Francisco to Clarksville (Tennessee) | 1,922.94 mi (3,094.67 km) |
| South San Francisco to Clawson (Michigan) | 2,083.79 mi (3,353.53 km) |
| South San Francisco to Clay (Alabama) | 2,016.17 mi (3,244.71 km) |
| South San Francisco to Clayton (California) | 33.26 mi (53.53 km) |
| South San Francisco to Clayton (Missouri) | 1,736.02 mi (2,793.85 km) |
| South San Francisco to Clayton (North Carolina) | 2,418.70 mi (3,892.52 km) |
| South San Francisco to Clayton (Ohio) | 2,042.35 mi (3,286.84 km) |
| South San Francisco to Clearfield (Utah) | 603.68 mi (971.53 km) |
| South San Francisco to Clearlake (California) | 90.91 mi (146.31 km) |
| South San Francisco to Clearwater (Florida) | 2,378.45 mi (3,827.75 km) |
| South San Francisco to Cleburne (Texas) | 1,456.84 mi (2,344.56 km) |
| South San Francisco to Clemmons (North Carolina) | 2,307.37 mi (3,713.35 km) |
