| South San Francisco to Darby (Pennsylvania) | 2,514.96 mi (4,047.44 km) |
| South San Francisco to Dardenne Prairie (Missouri) | 1,713.52 mi (2,757.65 km) |
| South San Francisco to Darien (Illinois) | 1,839.90 mi (2,961.03 km) |
| South San Francisco to Davenport (Iowa) | 1,705.04 mi (2,744.00 km) |
| South San Francisco to Davidson (North Carolina) | 2,294.13 mi (3,692.04 km) |
| South San Francisco to Davie (Florida) | 2,574.34 mi (4,143.00 km) |
| South San Francisco to Davis (California) | 72.50 mi (116.69 km) |
| South San Francisco to Dayton (Nevada) | 190.12 mi (305.97 km) |
| South San Francisco to Dayton (Ohio) | 2,049.99 mi (3,299.13 km) |
| South San Francisco to Daytona Beach (Florida) | 2,432.67 mi (3,915.01 km) |
| South San Francisco to De Pere (Wisconsin) | 1,835.12 mi (2,953.33 km) |
| South San Francisco to De Witt (New York) | 2,437.02 mi (3,922.00 km) |
| South San Francisco to Dearborn (Michigan) | 2,081.75 mi (3,350.26 km) |
| South San Francisco to Dearborn Heights (Michigan) | 2,078.48 mi (3,344.99 km) |
| South San Francisco to DeBary (Florida) | 2,429.67 mi (3,910.17 km) |
