| South San Francisco to Delaware (Ohio) | 2,104.04 mi (3,386.13 km) |
| South San Francisco to Delhi (California) | 91.36 mi (147.03 km) |
| South San Francisco to Delray Beach (Florida) | 2,572.66 mi (4,140.30 km) |
| South San Francisco to Deltona (Florida) | 2,435.00 mi (3,918.76 km) |
| South San Francisco to Deming (New Mexico) | 908.87 mi (1,462.68 km) |
| South San Francisco to Denison (Texas) | 1,469.41 mi (2,364.78 km) |
| South San Francisco to Dent (Ohio) | 2,031.92 mi (3,270.06 km) |
| South San Francisco to Denton (Texas) | 1,450.93 mi (2,335.05 km) |
| South San Francisco to Dentsville (South Carolina) | 2,316.05 mi (3,727.33 km) |
| South San Francisco to Denver (Colorado) | 955.46 mi (1,537.67 km) |
| South San Francisco to Depew (New York) | 2,306.29 mi (3,711.61 km) |
| South San Francisco to Derby (Connecticut) | 2,607.45 mi (4,196.28 km) |
| South San Francisco to Derby (Kansas) | 1,373.30 mi (2,210.11 km) |
| South San Francisco to Des Moines (Iowa) | 1,549.69 mi (2,493.98 km) |
| South San Francisco to Des Moines (Washington) | 672.82 mi (1,082.80 km) |
