| South San Francisco to Eagan (Minnesota) | 1,588.59 mi (2,556.60 km) |
| South San Francisco to Eagle (Idaho) | 524.76 mi (844.52 km) |
| South San Francisco to Eagle Mountain (Utah) | 588.01 mi (946.31 km) |
| South San Francisco to Eagle Pass (Texas) | 1,406.13 mi (2,262.94 km) |
| South San Francisco to Easley (South Carolina) | 2,212.10 mi (3,560.02 km) |
| South San Francisco to East Bakersfield (California) | 247.38 mi (398.11 km) |
| South San Francisco to East Bethel (Minnesota) | 1,592.18 mi (2,562.37 km) |
| South San Francisco to East Chicago (Indiana) | 1,867.43 mi (3,005.34 km) |
| South San Francisco to East Cleveland (Ohio) | 2,170.55 mi (3,493.16 km) |
| South San Francisco to East Glenville (New York) | 2,546.59 mi (4,098.35 km) |
| South San Francisco to East Grand Rapids (Michigan) | 1,957.75 mi (3,150.69 km) |
| South San Francisco to East Hemet (California) | 409.75 mi (659.42 km) |
| South San Francisco to East Highland Park (Virginia) | 2,440.19 mi (3,927.10 km) |
| South San Francisco to East Honolulu (Hawaii) | 2,385.35 mi (3,838.86 km) |
| South San Francisco to East Islip (New York) | 2,610.42 mi (4,201.06 km) |
