| South San Francisco to Eatontown (New Jersey) | 2,571.95 mi (4,139.16 km) |
| South San Francisco to Eau Claire (Wisconsin) | 1,669.78 mi (2,687.26 km) |
| South San Francisco to Echelon (New Jersey) | 2,529.77 mi (4,071.27 km) |
| South San Francisco to Eden (North Carolina) | 2,333.40 mi (3,755.24 km) |
| South San Francisco to Eden Prairie (Minnesota) | 1,574.56 mi (2,534.00 km) |
| South San Francisco to Edgewater (Florida) | 2,448.33 mi (3,940.20 km) |
| South San Francisco to Edgewater (New Jersey) | 2,568.71 mi (4,133.95 km) |
| South San Francisco to Edgewood (Maryland) | 2,468.38 mi (3,972.47 km) |
| South San Francisco to Edgewood (Washington) | 661.75 mi (1,064.98 km) |
| South San Francisco to Edina (Minnesota) | 1,579.79 mi (2,542.43 km) |
| South San Francisco to Edinburg (Texas) | 1,616.03 mi (2,600.76 km) |
| South San Francisco to Edmond (Oklahoma) | 1,388.47 mi (2,234.52 km) |
| South San Francisco to Edmonds (Washington) | 701.84 mi (1,129.50 km) |
| South San Francisco to Edwards (Colorado) | 862.39 mi (1,387.88 km) |
| South San Francisco to Edwardsville (Illinois) | 1,752.95 mi (2,821.10 km) |
