| South San Francisco to Frederick (Colorado) | 952.11 mi (1,532.28 km) |
| South San Francisco to Frederick (Maryland) | 2,409.81 mi (3,878.22 km) |
| South San Francisco to Fredericksburg (Texas) | 1,437.74 mi (2,313.81 km) |
| South San Francisco to Fredericksburg (Virginia) | 2,422.95 mi (3,899.37 km) |
| South San Francisco to Frederickson (Washington) | 652.10 mi (1,049.45 km) |
| South San Francisco to Freeport (Illinois) | 1,754.05 mi (2,822.86 km) |
| South San Francisco to Freeport (New York) | 2,591.05 mi (4,169.89 km) |
| South San Francisco to Freeport (Texas) | 1,667.11 mi (2,682.95 km) |
| South San Francisco to Fremont (California) | 25.40 mi (40.88 km) |
| South San Francisco to Fremont (Nebraska) | 1,400.67 mi (2,254.15 km) |
| South San Francisco to Fremont (Ohio) | 2,092.89 mi (3,368.18 km) |
| South San Francisco to French Valley (California) | 409.10 mi (658.38 km) |
| South San Francisco to Fresno (California) | 156.49 mi (251.85 km) |
| South San Francisco to Fresno (Texas) | 1,642.32 mi (2,643.06 km) |
| South San Francisco to Fridley (Minnesota) | 1,586.61 mi (2,553.39 km) |
