| South San Francisco to Friendly (Maryland) | 2,443.29 mi (3,932.10 km) |
| South San Francisco to Friendswood (Texas) | 1,657.63 mi (2,667.70 km) |
| South San Francisco to Frisco (Texas) | 1,469.81 mi (2,365.43 km) |
| South San Francisco to Front Royal (Virginia) | 2,376.74 mi (3,824.99 km) |
| South San Francisco to Fruit Cove (Florida) | 2,378.68 mi (3,828.11 km) |
| South San Francisco to Fruita (Colorado) | 747.68 mi (1,203.27 km) |
| South San Francisco to Fruitville (Florida) | 2,415.14 mi (3,886.80 km) |
| South San Francisco to Fuller Heights (Florida) | 2,421.90 mi (3,897.68 km) |
| South San Francisco to Fullerton (California) | 362.19 mi (582.88 km) |
| South San Francisco to Fullerton (Pennsylvania) | 2,493.74 mi (4,013.29 km) |
| South San Francisco to Fulshear (Texas) | 1,615.40 mi (2,599.74 km) |
| South San Francisco to Fulton (Missouri) | 1,647.55 mi (2,651.47 km) |
| South San Francisco to Fulton (New York) | 2,417.85 mi (3,891.15 km) |
| South San Francisco to Fuquay-Varina (North Carolina) | 2,402.31 mi (3,866.14 km) |
| South San Francisco to Gadsden (Alabama) | 2,041.89 mi (3,286.10 km) |
