| South San Francisco to La Quinta (California) | 441.70 mi (710.84 km) |
| South San Francisco to La Riviera (California) | 85.71 mi (137.93 km) |
| South San Francisco to La Vergne (Tennessee) | 1,974.20 mi (3,177.16 km) |
| South San Francisco to La Verne (California) | 356.73 mi (574.10 km) |
| South San Francisco to La Vista (Nebraska) | 1,421.97 mi (2,288.44 km) |
| South San Francisco to Lacey (Washington) | 649.23 mi (1,044.84 km) |
| South San Francisco to Lackawanna (New York) | 2,300.52 mi (3,702.32 km) |
| South San Francisco to Laconia (New Hampshire) | 2,660.80 mi (4,282.14 km) |
| South San Francisco to Ladera Ranch (California) | 390.36 mi (628.23 km) |
| South San Francisco to Ladson (South Carolina) | 2,386.27 mi (3,840.34 km) |
| South San Francisco to Lady Lake (Florida) | 2,395.29 mi (3,854.84 km) |
| South San Francisco to Lafayette (California) | 23.25 mi (37.41 km) |
| South San Francisco to Lafayette (Colorado) | 944.66 mi (1,520.28 km) |
| South San Francisco to Lafayette (Indiana) | 1,905.23 mi (3,066.17 km) |
| South San Francisco to Lafayette (Louisiana) | 1,807.38 mi (2,908.70 km) |
