| South San Francisco to Laredo (Texas) | 1,500.11 mi (2,414.19 km) |
| South San Francisco to Largo (Florida) | 2,380.15 mi (3,830.48 km) |
| South San Francisco to Largo (Maryland) | 2,448.56 mi (3,940.58 km) |
| South San Francisco to Larkspur (California) | 20.65 mi (33.23 km) |
| South San Francisco to Las Cruces (New Mexico) | 956.70 mi (1,539.65 km) |
| South San Francisco to Las Vegas (Nevada) | 406.96 mi (654.93 km) |
| South San Francisco to Las Vegas (New Mexico) | 962.76 mi (1,549.42 km) |
| South San Francisco to Latham (New York) | 2,556.70 mi (4,114.61 km) |
| South San Francisco to Lathrop (California) | 61.41 mi (98.83 km) |
| South San Francisco to Lauderdale Lakes (Florida) | 2,576.03 mi (4,145.72 km) |
| South San Francisco to Lauderhill (Florida) | 2,575.06 mi (4,144.16 km) |
| South San Francisco to Laurel (Florida) | 2,421.41 mi (3,896.89 km) |
| South San Francisco to Laurel (Maryland) | 2,443.58 mi (3,932.57 km) |
| South San Francisco to Laurel (Mississippi) | 1,924.40 mi (3,097.03 km) |
| South San Francisco to Laurel (Virginia) | 2,432.81 mi (3,915.23 km) |
