| South San Francisco to Leland (North Carolina) | 2,471.96 mi (3,978.24 km) |
| South San Francisco to Lemay (Missouri) | 1,739.55 mi (2,799.53 km) |
| South San Francisco to Lemon Grove (California) | 455.94 mi (733.77 km) |
| South San Francisco to Lemon Hill (California) | 79.36 mi (127.71 km) |
| South San Francisco to Lemont (Illinois) | 1,840.07 mi (2,961.30 km) |
| South San Francisco to Lemoore (California) | 172.47 mi (277.57 km) |
| South San Francisco to Lenexa (Kansas) | 1,494.36 mi (2,404.93 km) |
| South San Francisco to Lennox (California) | 343.01 mi (552.02 km) |
| South San Francisco to Lenoir (North Carolina) | 2,248.29 mi (3,618.27 km) |
| South San Francisco to Leominster (Massachusetts) | 2,658.39 mi (4,278.27 km) |
| South San Francisco to Leon Valley (Texas) | 1,476.47 mi (2,376.14 km) |
| South San Francisco to Levelland (Texas) | 1,158.64 mi (1,864.64 km) |
| South San Francisco to Levittown (New York) | 2,593.75 mi (4,174.24 km) |
| South San Francisco to Levittown (Pennsylvania) | 2,532.77 mi (4,076.10 km) |
| South San Francisco to Lewisburg (Tennessee) | 1,971.55 mi (3,172.91 km) |
