| South San Francisco to Lombard (Illinois) | 1,837.78 mi (2,957.61 km) |
| South San Francisco to Lomita (California) | 352.18 mi (566.79 km) |
| South San Francisco to Lompoc (California) | 233.54 mi (375.84 km) |
| South San Francisco to London (Ohio) | 2,088.89 mi (3,361.74 km) |
| South San Francisco to Lone Tree (Colorado) | 954.97 mi (1,536.87 km) |
| South San Francisco to Long Beach (California) | 357.52 mi (575.37 km) |
| South San Francisco to Long Beach (Mississippi) | 1,958.98 mi (3,152.67 km) |
| South San Francisco to Long Beach (New York) | 2,587.78 mi (4,164.62 km) |
| South San Francisco to Long Branch (New Jersey) | 2,575.19 mi (4,144.37 km) |
| South San Francisco to Longmont (Colorado) | 945.60 mi (1,521.79 km) |
| South San Francisco to Longview (Texas) | 1,597.19 mi (2,570.44 km) |
| South San Francisco to Longview (Washington) | 587.42 mi (945.36 km) |
| South San Francisco to Longwood (Florida) | 2,433.67 mi (3,916.61 km) |
| South San Francisco to Lorain (Ohio) | 2,140.17 mi (3,444.28 km) |
| South San Francisco to Lorton (Virginia) | 2,430.99 mi (3,912.30 km) |
