| South San Francisco to Oakleaf Plantation (Florida) | 2,364.86 mi (3,805.87 km) |
| South San Francisco to Oakley (California) | 45.96 mi (73.96 km) |
| South San Francisco to Oakton (Virginia) | 2,423.62 mi (3,900.44 km) |
| South San Francisco to Oakville (Missouri) | 1,738.49 mi (2,797.82 km) |
| South San Francisco to Oatfield (Oregon) | 536.15 mi (862.85 km) |
| South San Francisco to Ocala (Florida) | 2,375.73 mi (3,823.37 km) |
| South San Francisco to Ocean Acres (New Jersey) | 2,568.41 mi (4,133.46 km) |
| South San Francisco to Ocean City (New Jersey) | 2,559.00 mi (4,118.32 km) |
| South San Francisco to Ocean Pines (Maryland) | 2,544.70 mi (4,095.29 km) |
| South San Francisco to Ocean Pointe (Hawaii) | 2,400.67 mi (3,863.51 km) |
| South San Francisco to Ocean Springs (Mississippi) | 1,978.32 mi (3,183.80 km) |
| South San Francisco to Oceanside (California) | 419.90 mi (675.76 km) |
| South San Francisco to Oceanside (New York) | 2,588.67 mi (4,166.07 km) |
| South San Francisco to Ocoee (Florida) | 2,427.23 mi (3,906.26 km) |
| South San Francisco to Oconomowoc (Wisconsin) | 1,811.85 mi (2,915.89 km) |
