| South San Francisco to Owosso (Michigan) | 2,029.99 mi (3,266.96 km) |
| South San Francisco to Oxford (Alabama) | 2,058.73 mi (3,313.21 km) |
| South San Francisco to Oxford (Mississippi) | 1,842.59 mi (2,965.36 km) |
| South San Francisco to Oxford (Ohio) | 2,024.12 mi (3,257.50 km) |
| South San Francisco to Oxnard (California) | 299.77 mi (482.43 km) |
| South San Francisco to Oxon Hill (Maryland) | 2,442.41 mi (3,930.68 km) |
| South San Francisco to Ozark (Alabama) | 2,121.93 mi (3,414.91 km) |
| South San Francisco to Ozark (Missouri) | 1,598.19 mi (2,572.04 km) |
| South San Francisco to Pace (Florida) | 2,060.90 mi (3,316.71 km) |
| South San Francisco to Pacific Grove (California) | 76.51 mi (123.13 km) |
| South San Francisco to Pacifica (California) | 4.35 mi (7.00 km) |
| South San Francisco to Paducah (Kentucky) | 1,845.15 mi (2,969.48 km) |
| South San Francisco to Pahrump (Nevada) | 368.09 mi (592.38 km) |
| South San Francisco to Painesville (Ohio) | 2,185.75 mi (3,517.62 km) |
| South San Francisco to Palatine (Illinois) | 1,835.74 mi (2,954.34 km) |
