| South San Francisco to Reedley (California) | 179.23 mi (288.44 km) |
| South San Francisco to Reidsville (North Carolina) | 2,340.08 mi (3,765.99 km) |
| South San Francisco to Reisterstown (Maryland) | 2,440.85 mi (3,928.17 km) |
| South San Francisco to Rendon (Texas) | 1,461.07 mi (2,351.37 km) |
| South San Francisco to Reno (Nevada) | 190.87 mi (307.17 km) |
| South San Francisco to Renton (Washington) | 678.91 mi (1,092.60 km) |
| South San Francisco to Republic (Missouri) | 1,584.44 mi (2,549.91 km) |
| South San Francisco to Reston (Virginia) | 2,420.38 mi (3,895.22 km) |
| South San Francisco to Revere (Massachusetts) | 2,698.15 mi (4,342.25 km) |
| South San Francisco to Rexburg (Idaho) | 699.92 mi (1,126.41 km) |
| South San Francisco to Reynoldsburg (Ohio) | 2,121.92 mi (3,414.90 km) |
| South San Francisco to Rialto (California) | 372.71 mi (599.82 km) |
| South San Francisco to Richardson (Texas) | 1,480.22 mi (2,382.18 km) |
| South San Francisco to Richfield (Minnesota) | 1,583.39 mi (2,548.22 km) |
| South San Francisco to Richfield (Wisconsin) | 1,824.69 mi (2,936.56 km) |
