| South San Francisco to Shelbyville (Tennessee) | 1,989.08 mi (3,201.11 km) |
| South San Francisco to Shelton (Connecticut) | 2,604.92 mi (4,192.22 km) |
| South San Francisco to Shelton (Washington) | 661.80 mi (1,065.06 km) |
| South San Francisco to Shenandoah (Louisiana) | 1,857.82 mi (2,989.87 km) |
| South San Francisco to Shepherdsville (Kentucky) | 1,991.09 mi (3,204.34 km) |
| South San Francisco to Sheridan (Wyoming) | 940.29 mi (1,513.25 km) |
| South San Francisco to Sherman (Texas) | 1,470.16 mi (2,365.99 km) |
| South San Francisco to Sherrelwood (Colorado) | 949.12 mi (1,527.46 km) |
| South San Francisco to Sherwood (Arkansas) | 1,687.39 mi (2,715.60 km) |
| South San Francisco to Sherwood (Oregon) | 532.85 mi (857.54 km) |
| South San Francisco to Shiloh (Illinois) | 1,759.05 mi (2,830.91 km) |
| South San Francisco to Shiloh (Ohio) | 2,047.99 mi (3,295.91 km) |
| South San Francisco to Shiloh (Pennsylvania) | 2,434.80 mi (3,918.43 km) |
| South San Francisco to Shirley (New York) | 2,625.44 mi (4,225.23 km) |
| South San Francisco to Shively (Kentucky) | 1,982.30 mi (3,190.20 km) |
