| South San Francisco to Shoreline (Washington) | 698.03 mi (1,123.38 km) |
| South San Francisco to Shoreview (Minnesota) | 1,592.57 mi (2,563.00 km) |
| South San Francisco to Shorewood (Illinois) | 1,828.69 mi (2,943.00 km) |
| South San Francisco to Shorewood (Wisconsin) | 1,842.54 mi (2,965.29 km) |
| South San Francisco to Short Hills (New Jersey) | 2,551.72 mi (4,106.59 km) |
| South San Francisco to Short Pump (Virginia) | 2,426.47 mi (3,905.03 km) |
| South San Francisco to Show Low (Arizona) | 730.21 mi (1,175.16 km) |
| South San Francisco to Shreveport (Louisiana) | 1,651.25 mi (2,657.42 km) |
| South San Francisco to Sicklerville (New Jersey) | 2,531.40 mi (4,073.89 km) |
| South San Francisco to Sidney (Ohio) | 2,046.94 mi (3,294.23 km) |
| South San Francisco to Sierra Madre (California) | 343.09 mi (552.14 km) |
| South San Francisco to Sierra Vista (Arizona) | 805.77 mi (1,296.76 km) |
| South San Francisco to Sierra Vista Southeast (Arizona) | 814.93 mi (1,311.51 km) |
| South San Francisco to Signal Hill (California) | 357.20 mi (574.86 km) |
| South San Francisco to Sikeston (Missouri) | 1,796.75 mi (2,891.58 km) |
