| South San Francisco to St. George (Utah) | 487.14 mi (783.98 km) |
| South San Francisco to St. Helens (Oregon) | 567.17 mi (912.77 km) |
| South San Francisco to St. James (New York) | 2,610.08 mi (4,200.52 km) |
| South San Francisco to St. John (Indiana) | 1,867.48 mi (3,005.42 km) |
| South San Francisco to St. Joseph (Missouri) | 1,489.22 mi (2,396.68 km) |
| South San Francisco to St. Louis (Missouri) | 1,740.65 mi (2,801.31 km) |
| South San Francisco to St. Louis Park (Minnesota) | 1,580.13 mi (2,542.98 km) |
| South San Francisco to St. Marys (Georgia) | 2,363.10 mi (3,803.04 km) |
| South San Francisco to St. Marys (Pennsylvania) | 2,327.47 mi (3,745.70 km) |
| South San Francisco to St. Matthews (Kentucky) | 1,990.99 mi (3,204.19 km) |
| South San Francisco to St. Michael (Minnesota) | 1,567.04 mi (2,521.91 km) |
| South San Francisco to St. Paul (Minnesota) | 1,592.76 mi (2,563.29 km) |
| South San Francisco to St. Peter (Minnesota) | 1,544.98 mi (2,486.40 km) |
| South San Francisco to St. Peters (Missouri) | 1,720.01 mi (2,768.09 km) |
| South San Francisco to St. Petersburg (Florida) | 2,389.53 mi (3,845.58 km) |
