| South San Francisco to Stephenville (Texas) | 1,416.81 mi (2,280.14 km) |
| South San Francisco to Sterling (Colorado) | 1,048.36 mi (1,687.17 km) |
| South San Francisco to Sterling (Illinois) | 1,751.53 mi (2,818.81 km) |
| South San Francisco to Sterling (Virginia) | 2,416.46 mi (3,888.92 km) |
| South San Francisco to Sterling Heights (Michigan) | 2,089.66 mi (3,362.98 km) |
| South San Francisco to Steubenville (Ohio) | 2,229.43 mi (3,587.92 km) |
| South San Francisco to Stevens Point (Wisconsin) | 1,763.05 mi (2,837.36 km) |
| South San Francisco to Stevenson Ranch (California) | 310.92 mi (500.38 km) |
| South San Francisco to Stillwater (Minnesota) | 1,607.01 mi (2,586.23 km) |
| South San Francisco to Stillwater (Oklahoma) | 1,400.22 mi (2,253.43 km) |
| South San Francisco to Stockbridge (Georgia) | 2,149.78 mi (3,459.73 km) |
| South San Francisco to Stockton (California) | 64.49 mi (103.79 km) |
| South San Francisco to Stone Ridge (Virginia) | 2,409.68 mi (3,878.00 km) |
| South San Francisco to Stonecrest (Georgia) | 2,151.32 mi (3,462.21 km) |
| South San Francisco to Stony Brook (New York) | 2,610.91 mi (4,201.85 km) |
