| Cities | Distance |
|---|---|
| South San Francisco to Zanesville (Ohio) | 2,162.83 mi (3,480.73 km) |
| South San Francisco to Zephyrhills (Florida) | 2,402.18 mi (3,865.94 km) |
| South San Francisco to Zion (Illinois) | 1,844.87 mi (2,969.03 km) |
| South San Francisco to Zionsville (Indiana) | 1,936.78 mi (3,116.94 km) |