| South Valley to Spello | 5,831.84 mi (9,385.44 km) |
| South Valley to Spilamberto | 5,698.44 mi (9,170.76 km) |
| South Valley to Spilimbergo | 5,688.39 mi (9,154.58 km) |
| South Valley to Spinea | 5,693.61 mi (9,162.99 km) |
| South Valley to Spoleto | 5,843.52 mi (9,404.23 km) |
| South Valley to Spoltore | 5,910.77 mi (9,512.46 km) |
| South Valley to Spresiano | 5,682.90 mi (9,145.74 km) |
| South Valley to Squinzano | 6,151.52 mi (9,899.92 km) |
| South Valley to Statte | 6,114.52 mi (9,840.36 km) |
| South Valley to Stezzano | 5,597.23 mi (9,007.88 km) |
| South Valley to Strada | 5,754.19 mi (9,260.47 km) |
| South Valley to Stradella | 5,610.68 mi (9,029.52 km) |
| South Valley to Striano | 6,006.73 mi (9,666.90 km) |
| South Valley to Subiaco | 5,898.41 mi (9,492.57 km) |
| South Valley to Sulmona | 5,922.96 mi (9,532.08 km) |
