| Southampton to Cutrofiano | 1,200.40 mi (1,931.86 km) |
| Southampton to Dalmine | 621.67 mi (1,000.47 km) |
| Southampton to Deruta | 848.72 mi (1,365.89 km) |
| Southampton to Desenzano del Garda | 664.64 mi (1,069.63 km) |
| Southampton to Desio | 609.00 mi (980.09 km) |
| Southampton to Dolianova | 946.40 mi (1,523.09 km) |
| Southampton to Dolo | 725.70 mi (1,167.90 km) |
| Southampton to Domodossola | 552.72 mi (889.52 km) |
| Southampton to Dorgali | 902.77 mi (1,452.87 km) |
| Southampton to Dueville | 696.76 mi (1,121.32 km) |
| Southampton to Eboli | 1,060.83 mi (1,707.24 km) |
| Southampton to Elmas | 949.99 mi (1,528.86 km) |
| Southampton to Empoli | 760.78 mi (1,224.35 km) |
| Southampton to Enna | 1,199.88 mi (1,931.01 km) |
| Southampton to Eraclea | 743.41 mi (1,196.40 km) |
