| Southampton to Selargius | 953.63 mi (1,534.73 km) |
| Southampton to Selvazzano Dentro | 716.12 mi (1,152.48 km) |
| Southampton to Senago | 607.46 mi (977.61 km) |
| Southampton to Senigallia | 843.73 mi (1,357.86 km) |
| Southampton to Seravezza | 721.74 mi (1,161.53 km) |
| Southampton to Seregno | 606.89 mi (976.69 km) |
| Southampton to Seriate | 624.53 mi (1,005.09 km) |
| Southampton to Sermoneta | 940.60 mi (1,513.76 km) |
| Southampton to Serramanna | 937.24 mi (1,508.34 km) |
| Southampton to Serravalle Pistoiese | 747.72 mi (1,203.34 km) |
| Southampton to Sessa Aurunca | 989.84 mi (1,593.00 km) |
| Southampton to Sesto Calende | 582.46 mi (937.39 km) |
| Southampton to Sesto Fiorentino | 764.00 mi (1,229.54 km) |
| Southampton to Sesto San Giovanni | 613.37 mi (987.13 km) |
| Southampton to Sestri Levante | 679.16 mi (1,093.01 km) |
