| Southborough to Santa Venerina | 1,180.75 mi (1,900.24 km) |
| Southborough to Santeramo in Colle | 1,063.31 mi (1,711.23 km) |
| Southborough to Santo Stefano di Magra | 658.77 mi (1,060.19 km) |
| Southborough to Santo Stino di Livenza | 680.15 mi (1,094.60 km) |
| Southborough to Sarezzo | 592.89 mi (954.17 km) |
| Southborough to Sarno | 989.27 mi (1,592.08 km) |
| Southborough to Saronno | 554.43 mi (892.28 km) |
| Southborough to Sarzana | 662.79 mi (1,066.66 km) |
| Southborough to Sassari | 822.46 mi (1,323.62 km) |
| Southborough to Sasso Marconi | 690.23 mi (1,110.82 km) |
| Southborough to Sassuolo | 666.90 mi (1,073.27 km) |
| Southborough to Sava | 1,111.97 mi (1,789.54 km) |
| Southborough to Saviano | 980.61 mi (1,578.14 km) |
| Southborough to Savigliano | 564.00 mi (907.67 km) |
| Southborough to Savignano sul Panaro | 678.70 mi (1,092.26 km) |
