| Southborough to Savignano sul Rubicone | 745.12 mi (1,199.16 km) |
| Southborough to Savona | 607.41 mi (977.53 km) |
| Southborough to Scafati | 989.67 mi (1,592.72 km) |
| Southborough to Scalea | 1,082.17 mi (1,741.58 km) |
| Southborough to Scandiano | 661.55 mi (1,064.67 km) |
| Southborough to Scandicci | 721.23 mi (1,160.70 km) |
| Southborough to Schio | 631.51 mi (1,016.31 km) |
| Southborough to Sciacca | 1,132.70 mi (1,822.91 km) |
| Southborough to Scicli | 1,220.36 mi (1,963.98 km) |
| Southborough to Scordia | 1,194.67 mi (1,922.64 km) |
| Southborough to Scorze | 665.53 mi (1,071.06 km) |
| Southborough to Sedico | 641.78 mi (1,032.85 km) |
| Southborough to Sedriano | 559.33 mi (900.16 km) |
| Southborough to Segni | 890.59 mi (1,433.27 km) |
| Southborough to Segrate | 569.82 mi (917.03 km) |
