| Southborough to Selargius | 928.07 mi (1,493.58 km) |
| Southborough to Selvazzano Dentro | 661.98 mi (1,065.35 km) |
| Southborough to Senago | 559.75 mi (900.83 km) |
| Southborough to Senigallia | 792.46 mi (1,275.34 km) |
| Southborough to Seravezza | 677.48 mi (1,090.30 km) |
| Southborough to Seregno | 558.63 mi (899.03 km) |
| Southborough to Seriate | 574.49 mi (924.55 km) |
| Southborough to Sermoneta | 896.77 mi (1,443.21 km) |
| Southborough to Serramanna | 912.14 mi (1,467.94 km) |
| Southborough to Serravalle Pistoiese | 702.01 mi (1,129.77 km) |
| Southborough to Sessa Aurunca | 944.50 mi (1,520.03 km) |
| Southborough to Sesto Calende | 535.71 mi (862.14 km) |
| Southborough to Sesto Fiorentino | 717.47 mi (1,154.65 km) |
| Southborough to Sesto San Giovanni | 565.58 mi (910.21 km) |
| Southborough to Sestri Levante | 636.58 mi (1,024.48 km) |
