| Southborough to Spello | 810.11 mi (1,303.74 km) |
| Southborough to Spilamberto | 675.63 mi (1,087.32 km) |
| Southborough to Spilimbergo | 671.56 mi (1,080.77 km) |
| Southborough to Spinea | 670.94 mi (1,079.77 km) |
| Southborough to Spoleto | 822.64 mi (1,323.90 km) |
| Southborough to Spoltore | 887.41 mi (1,428.15 km) |
| Southborough to Spresiano | 661.60 mi (1,064.75 km) |
| Southborough to Squinzano | 1,127.51 mi (1,814.55 km) |
| Southborough to Statte | 1,090.50 mi (1,754.99 km) |
| Southborough to Stezzano | 573.91 mi (923.62 km) |
| Southborough to Strada | 734.33 mi (1,181.79 km) |
| Southborough to Stradella | 590.72 mi (950.67 km) |
| Southborough to Striano | 987.63 mi (1,589.43 km) |
| Southborough to Subiaco | 879.81 mi (1,415.92 km) |
| Southborough to Sulmona | 901.09 mi (1,450.17 km) |
