| Southend to Sacile | 659.93 mi (1,062.06 km) |
| Southend to Sala Consilina | 1,047.10 mi (1,685.14 km) |
| Southend to Salemi | 1,116.16 mi (1,796.28 km) |
| Southend to Salerno | 1,004.93 mi (1,617.28 km) |
| Southend to Salo | 607.88 mi (978.28 km) |
| Southend to Salsomaggiore Terme | 630.64 mi (1,014.91 km) |
| Southend to Saluzzo | 569.97 mi (917.29 km) |
| Southend to Salzano | 665.86 mi (1,071.60 km) |
| Southend to Samarate | 550.92 mi (886.62 km) |
| Southend to San Benedetto del Tronto | 854.78 mi (1,375.64 km) |
| Southend to San Biagio di Callalta | 668.25 mi (1,075.44 km) |
| Southend to San Bonifacio | 643.16 mi (1,035.07 km) |
| Southend to San Casciano in Val di Pesa | 730.41 mi (1,175.48 km) |
| Southend to San Cataldo | 1,167.43 mi (1,878.80 km) |
| Southend to San Cesareo | 881.23 mi (1,418.20 km) |
