| Southern Pines to Sacile | 4,608.84 mi (7,417.22 km) |
| Southern Pines to Sala Consilina | 4,932.06 mi (7,937.39 km) |
| Southern Pines to Salemi | 4,893.17 mi (7,874.79 km) |
| Southern Pines to Salerno | 4,884.21 mi (7,860.37 km) |
| Southern Pines to Salo | 4,535.59 mi (7,299.33 km) |
| Southern Pines to Salsomaggiore Terme | 4,535.39 mi (7,299.01 km) |
| Southern Pines to Saluzzo | 4,430.24 mi (7,129.78 km) |
| Southern Pines to Salzano | 4,606.09 mi (7,412.78 km) |
| Southern Pines to Samarate | 4,458.89 mi (7,175.89 km) |
| Southern Pines to San Benedetto del Tronto | 4,767.35 mi (7,672.32 km) |
| Southern Pines to San Biagio di Callalta | 4,612.63 mi (7,423.30 km) |
| Southern Pines to San Bonifacio | 4,574.27 mi (7,361.57 km) |
| Southern Pines to San Casciano in Val di Pesa | 4,624.76 mi (7,442.82 km) |
| Southern Pines to San Cataldo | 4,960.64 mi (7,983.37 km) |
| Southern Pines to San Cesareo | 4,756.93 mi (7,655.54 km) |
