| Southport to Sacile | 868.46 mi (1,397.65 km) |
| Southport to Sala Consilina | 1,259.70 mi (2,027.29 km) |
| Southport to Salemi | 1,326.69 mi (2,135.11 km) |
| Southport to Salerno | 1,217.68 mi (1,959.67 km) |
| Southport to Salo | 819.92 mi (1,319.53 km) |
| Southport to Salsomaggiore Terme | 843.45 mi (1,357.40 km) |
| Southport to Saluzzo | 780.53 mi (1,256.13 km) |
| Southport to Salzano | 876.11 mi (1,409.97 km) |
| Southport to Samarate | 763.73 mi (1,229.10 km) |
| Southport to San Benedetto del Tronto | 1,066.81 mi (1,716.87 km) |
| Southport to San Biagio di Callalta | 877.73 mi (1,412.57 km) |
| Southport to San Bonifacio | 854.72 mi (1,375.55 km) |
| Southport to San Casciano in Val di Pesa | 943.23 mi (1,517.98 km) |
| Southport to San Cataldo | 1,378.97 mi (2,219.24 km) |
| Southport to San Cesareo | 1,094.04 mi (1,760.68 km) |
