| Southport to Savignano sul Rubicone | 958.52 mi (1,542.59 km) |
| Southport to Savona | 827.19 mi (1,331.23 km) |
| Southport to Scafati | 1,206.32 mi (1,941.38 km) |
| Southport to Scalea | 1,298.30 mi (2,089.42 km) |
| Southport to Scandiano | 877.38 mi (1,412.01 km) |
| Southport to Scandicci | 938.04 mi (1,509.63 km) |
| Southport to Schio | 841.58 mi (1,354.39 km) |
| Southport to Sciacca | 1,352.96 mi (2,177.38 km) |
| Southport to Scicli | 1,440.26 mi (2,317.88 km) |
| Southport to Scordia | 1,414.28 mi (2,276.06 km) |
| Southport to Scorze | 873.96 mi (1,406.49 km) |
| Southport to Sedico | 847.39 mi (1,363.74 km) |
| Southport to Sedriano | 776.48 mi (1,249.62 km) |
| Southport to Segni | 1,108.08 mi (1,783.28 km) |
| Southport to Segrate | 786.24 mi (1,265.33 km) |
