| Southport to Spello | 1,025.79 mi (1,650.84 km) |
| Southport to Spilamberto | 890.90 mi (1,433.76 km) |
| Southport to Spilimbergo | 874.45 mi (1,407.29 km) |
| Southport to Spinea | 879.58 mi (1,415.55 km) |
| Southport to Spoleto | 1,038.78 mi (1,671.76 km) |
| Southport to Spoltore | 1,101.41 mi (1,772.54 km) |
| Southport to Spresiano | 868.53 mi (1,397.77 km) |
| Southport to Squinzano | 1,338.31 mi (2,153.80 km) |
| Southport to Statte | 1,302.72 mi (2,096.53 km) |
| Southport to Stezzano | 788.98 mi (1,269.74 km) |
| Southport to Strada | 951.27 mi (1,530.91 km) |
| Southport to Stradella | 808.17 mi (1,300.62 km) |
| Southport to Striano | 1,204.11 mi (1,937.83 km) |
| Southport to Subiaco | 1,096.78 mi (1,765.09 km) |
| Southport to Sulmona | 1,116.42 mi (1,796.70 km) |
