| Spokane to Storm Lake (Iowa) | 1,133.11 mi (1,823.56 km) |
| Spokane to Storrs (Connecticut) | 2,221.58 mi (3,575.28 km) |
| Spokane to Stoughton (Wisconsin) | 1,401.33 mi (2,255.23 km) |
| Spokane to Stow (Ohio) | 1,814.43 mi (2,920.04 km) |
| Spokane to Streamwood (Illinois) | 1,475.55 mi (2,374.66 km) |
| Spokane to Streator (Illinois) | 1,472.95 mi (2,370.48 km) |
| Spokane to Streetsboro (Ohio) | 1,816.62 mi (2,923.56 km) |
| Spokane to Strongsville (Ohio) | 1,791.77 mi (2,883.58 km) |
| Spokane to Stuart (Florida) | 2,446.48 mi (3,937.22 km) |
| Spokane to Stuarts Draft (Virginia) | 2,032.18 mi (3,270.48 km) |
| Spokane to Sturgis (Michigan) | 1,610.27 mi (2,591.48 km) |
| Spokane to Suamico (Wisconsin) | 1,412.37 mi (2,272.99 km) |
| Spokane to Sudley (Virginia) | 2,076.34 mi (3,341.54 km) |
| Spokane to Suffern (New York) | 2,155.42 mi (3,468.82 km) |
| Spokane to Suffolk (Virginia) | 2,192.26 mi (3,528.10 km) |
