| Spokane Valley to Enterprise (Nevada) | 811.70 mi (1,306.31 km) |
| Spokane Valley to Enumclaw (Washington) | 224.48 mi (361.27 km) |
| Spokane Valley to Ephrata (Pennsylvania) | 2,081.25 mi (3,349.44 km) |
| Spokane Valley to Erie (Colorado) | 802.38 mi (1,291.31 km) |
| Spokane Valley to Erie (Pennsylvania) | 1,840.37 mi (2,961.79 km) |
| Spokane Valley to Erlanger (Kentucky) | 1,730.82 mi (2,785.48 km) |
| Spokane Valley to Escanaba (Michigan) | 1,425.32 mi (2,293.83 km) |
| Spokane Valley to Escondido (California) | 1,003.81 mi (1,615.48 km) |
| Spokane Valley to Española (New Mexico) | 987.38 mi (1,589.03 km) |
| Spokane Valley to Essex (Maryland) | 2,098.28 mi (3,376.86 km) |
| Spokane Valley to Essex Junction (Vermont) | 2,097.25 mi (3,375.19 km) |
| Spokane Valley to Estelle (Louisiana) | 1,893.74 mi (3,047.67 km) |
| Spokane Valley to Estero (Florida) | 2,409.90 mi (3,878.35 km) |
| Spokane Valley to Euclid (Ohio) | 1,788.66 mi (2,878.57 km) |
| Spokane Valley to Eufaula (Alabama) | 1,999.57 mi (3,218.00 km) |
