| Spokane Valley to Scottsbluff (Nebraska) | 775.30 mi (1,247.72 km) |
| Spokane Valley to Scottsboro (Alabama) | 1,837.23 mi (2,956.73 km) |
| Spokane Valley to Scottsdale (Arizona) | 1,005.12 mi (1,617.59 km) |
| Spokane Valley to Scranton (Pennsylvania) | 2,066.54 mi (3,325.77 km) |
| Spokane Valley to Seabrook (Maryland) | 2,090.46 mi (3,364.27 km) |
| Spokane Valley to Seabrook (Texas) | 1,719.71 mi (2,767.61 km) |
| Spokane Valley to Seaford (New York) | 2,190.53 mi (3,525.32 km) |
| Spokane Valley to Seagoville (Texas) | 1,497.38 mi (2,409.80 km) |
| Spokane Valley to Seal Beach (California) | 961.96 mi (1,548.13 km) |
| Spokane Valley to Searcy (Arkansas) | 1,563.55 mi (2,516.28 km) |
| Spokane Valley to Seaside (California) | 797.78 mi (1,283.90 km) |
| Spokane Valley to SeaTac (Washington) | 236.58 mi (380.74 km) |
| Spokane Valley to Seattle (Washington) | 236.92 mi (381.28 km) |
| Spokane Valley to Sebastian (Florida) | 2,398.80 mi (3,860.49 km) |
| Spokane Valley to Sebring (Florida) | 2,372.01 mi (3,817.37 km) |
